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Pawase et al., 2024)

Roxas and Viswanathan 2018

10.1111/j.1365-2036.2009.04175.x 20 D'SouzaA

457 showed that pHLIP-Ku80 (), which was created by covalently conjugating pHLIPs with PNA targeting KU80 via disulfide bonds, could selectively reduce Ku80 expression under acidic conditions

This breakthrough has accelerated research into riboflavins role not only as a conventional dietary supplement to correct metabolic deficiencies, but also as a component of gene therapy approaches and enzyme-targeted precision medicine