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Recently, ten human patients with lumbar IVD disease treated with an intradiscal BMSC injection showed diminished pain and disability and a significantly elevated IVD water content (MRI) at the 1-year follow-up [98]

PMID 30969667

Specifically, the upregulation of ABCG2 expression and function in response to soluble uric acid in intestinal cell lines is dependent on PDZK1 at the transcriptional level