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Nature 448 , 474479 (2007)

Collectively, GGCT functions as a metabolic rheostat that orchestrates mitochondrial homeostasis through diverting Gln flux toward glutathione biosynthesis to fortify redox defense, while enhancing Glc-fueled TCA cycle anaplerosis to sustain cell proliferation

One of its proposed mechanisms of action is the preservation of glutathione levels in cardiomyocytes, thereby protecting against oxidative stress [99,100]

doi: 10.1016/j.celrep.2017.12.039 29 BonventoG.BolaosJ

Chelation is among the potential mechanisms that largely govern metal-tolerance in plant cells by maintaining low concentrations of free metals in cytoplasm