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Systemic inflammatory biomarkers and co-morbidities of chronic obstructive pulmonary disease

J Cell Biochem 122(12):19361945 Sas-Chen A et al (2020) Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping

MTHFR mutation also can increase environmental risks for psychiatric disorders, such as MDD through interaction between genetic and epigenetic factors

In addition, Fe 2+ accumulation in the mitochondria leads to a deficiency of the Fe-S clusters, resulting in increased ROS levels in the mitochondria, which may subsequently lead to pancreatic -cells ferroptosis due to the accumulation of lipid peroxides [12]

Thus, DNA methylation is involved not only in the differentiation and tissue-specific development of the retina, but also plays a crucial role in regulating gene expression throughout retinal development and aging