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Evaluation of cumulus mRNA expression The expression of genes related to oocyte maturation, hyaluronon synthase 2 ( HAS2 ) and tumor necrosis factor alpha-induced protein 6 ( TNFAIP6 ), and genes involved in regulation of the OCM, CBS , BHMT and MTR , were analyzed using real time reverse transcription polymerase chain reaction (RT-PCR)

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Furthermore, the protein disulfide isomerase (PDI) directly interacts with integrins, mediating disulfide-thiol exchange, resulting in conformational changes and activation (Popierlarski et al

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doi:10.1016/j.envint.2020.105974 Mannucci PM, Harari S, Franchini M