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Among the salient indications, inhaled NO is used for acute pulmonary vasoreactivity testing and severe hypoxia in pulmonary arterial hypertension (PAH), nitrates are used extensively in ischemic heart disease and heart failure, sGC stimulators and activators are used for PAH, and PDE5 inhibitors are used for erectile dysfunction, PAH and benign prostatic hyperplasia

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Functional medicine practitioners, like myself, use functional blood analysis and other tests to look at optimal ranges to help recognize even subclinical health challenges and risk of health problems

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In my clinic we use 900-1800 mg of NAC starting 6 months or more prior to conception