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These observations highlight differences between the immunogenicity of multivalent recombinant protein nanoparticles where immunogens are expressed, purified, and characterized ex vivo prior to delivery of a fixed antigen dose and repRNA, which enables streamlined manufacturing, but the final antigen dose depends on in vivo expression

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Mild injection-site reactions Localized redness, irritation, or discomfort at the injection site are most common

Lauria MW1 (1) Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil Diabetology & Metabolic Syndrome 2026: PO114 Introduction: Phase Angle (PA) measured by bioimpedance analysis (BIA) can be useful in assessing health status and cell membrane integrity in various medical conditions