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Moreover, ZnT4, Zip1, and Zip6 mRNA levels were inversely associated with CRP concentration, whereas ZnT4 and ZnT5 mRNA levels were characterized by an inverse correlation with TNF- [130]

6 , as no sign of evidence of distinctive hepatotoxicity was found in green tea treated rats, as this study showed no hepatic functional disorders based on the levels of ALT and AST in serum, as well as histological sections of the liver

Existing evidence demonstrate that the leukemic blasts and LSCs have significantly higher levels of OXPHOS compared to HSCs and OXPHOS inhibition by Venetoclax is effective in targeting AML cells ( This study provided proof of principle concept that Venetoclax+ HMA mediated LSC specific amino acid, OXPHOS and antioxidant pathways activation inhibition can serve as curative therapy