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From day 5 onward, all DSS-treated groups exhibited significant weight loss compared with the NC group, with the most severe reduction observed in the DSS model group

Furthermore, some researchers have used nano-cascade engineering to construct metal-organic supermolecules with p53-activating peptides and CeO 2 nanoparticles, which can activate the p53 signaling pathway and down-regulate the downstream gene GPX4 in vitro and in vivo, thereby inhibiting the development and progression of lung cancer [106]

Low-Dose Curcumin nanoparticles normalise blood pressure in male Wistar rats with Diet-Induced metabolic syndrome

Tail-vein injection of parental, control and Grpr -expressing cells demonstrated that GRPR expression alone is sufficient to promote lung metastasis (Fig