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After CPZ withdrawal, the brain undergoes spontaneous OPC differentiation and remyelination within 23 weeks 5,6

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These two steps (extraction and purification) need to be very controlled due to being vital for the bioactive assay, where impurities or chemical conformation of the molecule can affect the assay directly with false positives or contradictory results

Due to the different background between non-pregnant animals and pregnant animal, the self-interaction was filtered by using regression correlation r 2 0.9 and the gene expression deviation (TPM preg TPM reg ) 10

Das M, Calderon L, Singh D, Majumder S, Bazina L, Vaze N, et al