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Paired end reads were aligned using the Kallisto quant tool (Version 0.46.0) with WBcel235 as the reference genome

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Finally, the residue was dissolved in 50 L mobile phase (acetonitrile/water (80/20) with 0.05% v/v acetic acid) and analysed by LC/MS was carried out on a Agilent Technologies 1290 Infinity II UHPLC module coupled to a 6475 LC/TQ(triple quadrupole) tandem mass spectrometer controlled by Agilent OpenLab Control Panel (6475A) software (Agilent Technologies, Santa Clara, CA, USA)

Lenti- RRM2 shRNA vector was constructed using RRM2 shRNA oligonucleotides with LV 2N (U6/Puro) vector

Based on current related studies and investigations, diet interventions have now been found to play important roles in the treatment and prevention of PD