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demonstrated that AZD5363 effectively blocks tumor associated macrophage induced migration and epithelial mesenchymal transition in RCC cells by inhibiting AKT activity, suggesting its therapeutic potential for RCC (232)

Reminder All of the above describes compound-level research

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Additionally, they established that according to the WHO definition for MetS, each unit increase in log-transformed IGF-1 concentrations, was associated with a 90.5 % reduction in the risk of MetS [226]