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Additionally, DSIP attenuates ACTH and corticosterone release in response to stress, indicating an effect on the hypothalamic-pituitary-adrenal axis [8]

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Some interfere with natural insulin production, while others activate biological pathways that healthy cells use for growth and repair

Unlike recombinant GH therapy, sermorelin has not been strongly associated with severe fluid retention, insulin resistance, or joint pain in the short term, though long-term data are limited