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M., Lengyel, E

Semaglutide, a GLP-1 receptor agonist approved in 2021, demonstrated much greater weight loss than previous medications, which stimulated the development of poly-agonists that combine GLP-1 receptor agonism with GIP and glucagon receptor agonism

10.1016/j.neuropharm.2019.107742 70 ThijsR

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and other lipid soluble compounds which have chemical or biological activity