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Chelating agents of some embodiments include but are not limited to disodium ethylenediaminetetraacetate (EDTA), citric acid, salicylates (e.g., sodium salicylate, 5-methoxysalicylate and homovanilate), N-acyl derivatives of collagen, laureth-9 and N-amino acyl derivatives of beta-diketones (enamines) (Lee et al., Critical Reviews in Therapeutic Drug Carrier Systems, 1991, page 92

Although initially considered a waste product of aerobic glycolysis (e.g., the Warburg effect), lactate has been shown to serve as the primary carbon source for the TCA cycle in vivo, providing substrates, and thus electrons, for oxidative phosphorylation in normal tissue and tumors 2,3

For instance, in the reaction R + ArOH ArO + RH, a lower bond dissociation enthalpy facilitates hydrogen donation (158, 159)

Given that the incidence rates of depression, anxiety, and inferiority complex among patients with immune-mediated skin diseases are much higher than those in the general population (23), psychological intervention and support are indispensable components

While Health Secretary Robert F