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Chromatographic purification of active metabolites All six extracts were air-dried and their residues were then resuspended in methanol to be ready for applying onto thin layer chromatography (TLC) plate (10 10 cm Merck aluminum sheet, silica gel 60, layer thickness 0.2 mm)

Pro-Apoptotic Effects on Cancer Cells Before discussing the pro-apoptotic effects of ALA on tumor cells, it is essential to clarify that the roles and mechanisms of ROS in inducing cell damage and apoptosis differ between cancerous and normal cells [88]

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10.1016/s0040-4039(00)99750-8 320 WenY

B-017 inhibits apoptotic and necrotic signalling pathways in human cells To gain insight into the inhibitory effects of B-017, we examined its impact on cell death signalling in several mouse and human cell lines