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While ACP targets intra-articular inflammation, subchondral BMAC additionally addresses BMLs, and our findings over 12 months are consistent with the symptomatic improvements reported with ACP

Nevertheless, unnecessary biopsies of benign reactive lymph nodes should be avoided (162)

While semaglutide does not require dose adjustment for mild to moderate renal impairment, experience in patients with severe renal impairment is limited