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This is critical for maintaining a healthy immune system, as chronic oxidative stress can impair immune function and increase susceptibility to infections

In contrast, muscle contraction increases uptake of fatty acids from the circulation into muscle cells [23], which leads to a decrease in circulating fatty acids

For instance, SCFAs can inhibit NF-B activation and the secretion of inflammatory cytokines like TNF- in peripheral blood monocytes, neutrophils, and macrophages, thereby mitigating excessive immune responses