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Therefore, targeted activation of antioxidant systems, especially the GSH system, is an essential treatment strategy to protect cardiomyocytes against oxidative damage

Also, one of the metabolic targets of icatibant is ANPEP, which is a prognostic marker for prostate cancer [33]

302 This suggests that MAFLD progression involves iron overload, an imbalance in antioxidant defenses, and lipid peroxidation within in the ferroptosis signaling pathway

Similarly, manganese and copper are vital for mitochondrial and cytosolic SOD activity, and their deficiencies exacerbate oxidative stress and impair immune function [34,52,53,54]

Abbas AM, Elsamanoudy AZ