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Mucosal endothelium is now well recognized to play an active role in the pathogenesis of both forms of inflammatory bowel disease, Crohn's disease and ulcerative colitis

Synapse 70(12):479500

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Effects of des-aspartate-angiotensin I on the actions of angiotensin III in the renal and mesenteric vasculature of normo- and hypertensive rats

While current clinical and anecdotal evidence hasnt shown an increased risk, caution makes sense, especially if you have a history of cancer or concerns about tumors