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Under hypoxic stress, cancer cells not only adapt their own metabolism but also actively reprogram neighboring CAFs, establishing a metabolic symbiosis that facilitates tumor growth, survival, and resistance to therapy (128)

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*Correspondence: Roosmarijn E

At the protein level (Figs 1a and S1), GSTK and GSTO were found to be the most ubiquitously expressed GSTs, whereas GSTA showed exceptionally low expression in all the cell lines studied