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2024;121(21): e2316006121

In fungal infection models, upon macrophage uptake of Mucor circinelloides, ATF1 and ATF2 are activated to regulate a series of gene networks, including Chi1 and Aqp1, thus enhancing fungal survival within the phagosome

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This review will provide a comprehensive view of the role of miRNAs in the pathogenesis of ED and the potential value of miRNAs in the treatment of ED

The GHR belongs to the class 1 cytokine receptors which uses STAT as one of its principal secondary messengers, and the subsequent phosphorylation of two STAT5b molecules results in a phospo-STAT5b homodimer which translocate to the cell nucleus, binds to STAT5b recognition sites on the IGF1 gene promoter, and initiates transcription (Figure 3)