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doi: 10.1007/s00394-019-02105-2

Antioxidant Defense and Tissue Health Riboflavin is also a powerful antioxidant , playing a critical role in reducing oxidative stress and supporting: Skin and eye health Tissue repair and integrity Mucous membrane function A deficiency in riboflavin may cause symptoms such as: Cracked lips or corners of the mouth Sore throat Inflammation of the tongue and lining of the mouth Skin disorders and sensitivity to light Foods Rich in Vitamin B2 Animal-Based Sources Dairy products are among the best dietary sources of riboflavin: Milk Yogurt Cheese These not only support riboflavin intake but also provide calcium , protein , and other essential nutrients

Furthermore, the OA-associated acidic microenvironments (pH 6.67.2) promote M1 macrophage polarization through altered glucose metabolism, thereby augmenting their pro-inflammatory activity [11]

T., Cupples, L

Safety, tolerability, and pharmacokinetics of ibuprofenamine hydrochloride spray (NSAIDs), a new drug for rheumatoid arthritis and osteoarthritis, in healthy chinese subjects