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The Kihito formula, when combined with ChEIs therapy, significantly improved cognitive scores in Mini-Mental-State Examination Japanese (MMSE-J) evaluations, surpassing monotherapy outcomes (Watari et al., 2019)

10.1038/ng0594-13 Nat Genet

NPTAs inhibit A aggregation or facilitate A dissociation Aggregation and entanglement of A is one of the commonly accepted hypotheses for the pathogenesis of AD