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The precise mechanisms by which GSH depletion regulates apoptosis are, however, not clear

Our molecular docking results revealed that the free binding energies of the five core genes with puerarin were as follows: HIF1A-PUE ( 3.45 kcal/mol), mTOR-PUE ( 3.78 kcal/mol), PTGS2-PUE ( 4.44 kcal/mol), RELA-PUE ( 3.42 kcal/mol), and GSK3-PUE ( 3.03 kcal/mol)