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Summary: Seeing the Bigger Picture The question "does paracetamol affect gut microbiome" doesn't have a simple "yes or no" answer, but rather a "yes, but it's complicated." While it is significantly kinder to the gut lining than ibuprofen or aspirin, paracetamol still interacts with your microbial residents and puts a specific demand on your liver's antioxidant stores

Zinc supplementation has been shown to increase plasma antioxidant capacity, decrease plasma inflammatory cytokines and oxidative stress biomarkers, as well as NF-B activation (47)

discussion 63-4

The main potential benefits can include: That said, its always recommended to consult with a qualified medical professional before starting any new treatment or therapy