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The reaction was quenched by the addition of 5 Laemmli and 400 M mmPEG and incubation for 15 min on ice

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The antibodies prevent the B12 from binding to the intrinsic factor resulting in a deficiency

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There are also reports of ebselen conjugates with commonly used drugs, such as clioquinol, a compound known for its ability to chelate metal ions and inhibit A deposition