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At MC1R on melanocytes, MT-2 activates the cAMP-PKA-MITF-tyrosinase cascade, increasing eumelanin synthesis and skin pigmentation

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Interestingly, components of cholesterol efflux and fatty acid metabolism are regulated by miR-33a and miR-33b

For this reason, L-carnitine deficiency is quite common among vegetarians and even health-conscious people who simply avoid red meat