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The potent radical scavenger is a master at combatting aggressive oxygen and hydrogen radicals, which can otherwise lead to cell and tissue damage

Therefore, it is important to characterize the entire chain of the molecular events linking ocular hypertension and RGCs death in order to find the most sensitive and convenient target(s) for neuroprotective therapeutic intervention

Quercetin also exhibits the potential to inhibit atherosclerotic ferroptosis while serving as an antidepressant by targeting ferroptosis-related mechanisms ( 10 Conclusions and future perspectives In conclusion, studying the mechanisms of comorbidity through the perspective of ferroptosis is essential, with GPX4 and Nrf2 being highlighted as critical targets

PMID: 38175757 Cell RepPan-cancer tRNA-derived fragment CAT1 coordinates RBPMS to stabilize NOTCH2 mRNA to promote tumorigenesis