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In CKD, there is a gradual decrease in kidney function, resulting in a decrease in EPO synthesis and inadequate stimulation of the creation of RBCs (erythropoiesis)

When skin is damaged, ECM proteins undergo a series of finely regulated repair processes aimed at restoring skin integrity, structural stability, and internal environmental balance

Thus, it remains a pressing clinical challenge to find ways to prevent adverse ventricular remodeling and delay heart failure

Therefore, MSCs may regulate cell death through their extracellular vesicles (EVs) and interactions with immune cells

This circular genome is organized into discrete nucleoids in MM