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The background of the figure merges two very well-known, almost archetypical, symbols of systems thinking: the Vitruvian Man (Le proporzioni del corpo umano secondo Vitruvio) and the Taiji (the literal translation of which is great pole)

For example, P301S mice have been observed to spend relatively more time in open arms of EPM or in the center area of OFT compared to wildtype control, while they may exhibit sexual dimorphism (Dumont et al., 2011

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Symptoms include vomiting, diarrhea, jaundice (yellowing of the skin and eyes), and, in severe cases, neurological issues like seizures

Hepatocyte growth factor mediates mesenchymal stem cellinduced recovery in multiple sclerosis models