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Orthopedic applications represent another emerging area, with studies demonstrating that GHK-Cu enhances bone healing in fracture models through stimulation of osteoblast differentiation, increased bone matrix protein synthesis, and enhanced angiogenesis in healing bone tissues

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3.4 The target network and molecular docking with SIRT1 of GHK-Cu A flowchart of the drug target screening based on network pharmacology is shown in Figure 5A

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