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For physicians, the challenge is not simply determining whether a peptide works

10.3389/fphar.2020.586806 49 WhitmoreK

Pharmacologic inhibition of host phosphodiesterase-4 improves isoniazid-mediated clearance of mycobacterium tuberculosis

First, mechanistic studies should integrate single-cell spatial transcriptomics and mitochondrial metabolomics to map ferroptosis pathways in OPCs, mature oligodendrocytes, and microglia within periventricular white matter of infants with PVL