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[24] revealed neuroprotection and neuroregeneration by GPE in which the tripeptide enhanced proliferation and migration in mouse neural stem cells (NSCs) following injury involving 13.5 Days post-conception (dpc) mouse embryos

GHK-Cu provides broader systemic benefits and strong mechanistic rationale but requires accepting the limitations of its research compound status

However, long-term human studies specifically examining extended use remain limited

The translation from mouse to human senolytic therapy has proven challenging for several reasons: species differences in senescent cell biology

These findings are encouraging, though more large-scale trials are needed