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Inflammatory Acne or Rashes Although uncommon, a deficiency in B12 may lead to: Persistent acne-like eruptions Seborrheic dermatitis-like rashes (scaly, red patches, especially around the nose or scalp) Increased skin sensitivity and redness Some people experience inflammatory breakouts due to an imbalance in the skins bacterial profile, worsened by low B12 levels

Genes encoding stress and defense response-related proteins including GSTs were up-regulated consistently in infected plants (Soria-Guerra et al., 2010)

PMID:30692251

10.1111/J.1525-1438.2006.00524.X 59 KimK

Limitations of the therapeutic use of superoxide dismutase Due to the instability, high immunogenicity, low cellular uptake and less in vivo circulation of the half-life of superoxide dismutase, their clinical use as therapeutic agents is very limited