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A comprehensive review of recent clinical data highlights that while folate deficiency is common among individuals with ASD, maternal folic acid supplementation does not correlate with higher risk of the disorder, indeed folate therapy has been associated with improved neurodevelopmental outcomes (Vasconcelos et al., 2025)

SCFAs bind to the G protein-coupled receptor 41 (GPR41) on the surface of CD8 + T cells, inducing the activation of extracellular signal-regulated kinases (ERK) to enhance glucose uptake and glycolysis, thereby enhancing the effector function of CD8 + T cells

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doi:10.1016/j.jacl.2011.03.002

doi: 10.1016/j.phrs.2021.105874