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Pathway 4 Amylin (Cagrilintide) Amylin receptors (AMY1R, AMY3R heterodimers of the calcitonin receptor with RAMP1/RAMP3) are activated primarily in the area postrema, with secondary action in the NTS (Lau et al., 2021)

Experiments using isolated cells were performed only with tissues from Fischer 344 rats, and lactate dehydrogenase release was used as the measure of cellular toxicity

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2019;8doi:10.12688/f1000research.15318.1 Delitala AP, Capobianco G, Delitala G, Cherchi PL, Dessole S