Stages of Sleep Deprivation Sleep deprivation doesnt hit all at onceit develops in stages, each with worsening effects: Stage 1: 24 Hours Without Sleep You might start to feel less alert, have trouble focusing, and have poorer judgment after a full day of not getting any sleep

Thank you to our sponsors AG1 (Athletic Greens): InsideTracker: Thesis: Supplements from Momentous For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Aggression, Types of Aggression (00:03:33) Sponsors (00:08:29) Neural Circuits for Aggression, Hydraulic Pressure Model (00:15:50) Brain Regions Controlling Aggression, Ventromedial Hypothalamus (VMH) (00:22:14) Psychiatric Disorders & Aggression (00:23:36) Stimulation of the VMH, Estrogen Receptors & Aggression (00:31:57) Neural Circuits Mediating Physical Acts of Aggression, Biting (0:35:56) Testosterone & Competitiveness/Estrogen & Aggression (00:43:00) Sunlight, Melatonin & Aggression (00:45:46) Cortisol, Serotonin & Aggressive Behaviors (00:51:56) Tool: Omega-3 Supplementation & Mood (00:54:18) Tool: Sunlight, Sauna & Cortisol Reduction (00:55:54) Tool: Ashwagandha & Cortisol Reduction (00:57:06) Tool: Seasonality/Sunlight, Genetic Variation in Estrogen Sensitivity (01:00:37) Testosterone & Aggression, Competitive Work Environments (01:05:07) Testosterone, Amygdala, Challenge & Effort (01:09:27) Caffeine, Alcohol & Impulsivity (01:13:15) Tool: Caffeinated Alcohol Beverages, Impulsivity & Aggression (01:17:18) Tool: ADHD, Acetyl-L Carnitine & Aggressive Behavior (01:24:10) Factors Affecting the Hydraulic Pressure Model of Aggression (01:25:44) Book by Dr

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GSH levels are highest in liver tissue, which is also a hub for lipid production