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This inhibition mode in hTYR is noteworthy, as it suggests that the search for and optimization of efficient and safe peptide-based inhibitors may become a key direction in the development of human tyrosinase inhibitors

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REDEFINE 2: Efficacy in Type 2 Diabetes REDEFINE 2, announced in March 2025, addressed a distinct population: 1,206 adults with obesity or overweight and type 2 diabetes across 12 countries, randomised in a 3:1 ratio to CagriSema or placebo for 68 weeks

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Future research should incorporate larger multidisciplinary viewpoints in addition to molecular and clinical issues