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mild, moderate, severe, and very severe ( In one survey of 1418 ME/CFS patients ( Diagnostic criteria for ME/CFS The original neurological classification of ME/CFS In 1969, the World Health Organisation (WHO) classified ME/CFS as a neurological disease ( Available diagnostic criteria Despite its high prevalence, there are still no universally accepted clinical criteria to characterise ME/CFS, making early and accurate diagnosis difficult ( Figure 3

Rothman KJ, Gallacher JE, Hatch EE

Figure 1 TMAO and Inflammation-Immunity AS is a chronic inflammatory disease in which the innate and adaptive immune systems respond to many endogenous and exogenous molecules and highly diverse challenges (Ross, 1999

The high dose of L-carnitine (100 mg/kg) exhibited significant improvement of all the aforementioned parameters as compared to the lower doses (25 and 50 mg/kg)

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