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Description

Individuals with the syndrome show sudden gain in weight around their mid-torso, chest, abdomen, and face, often with thin legs and arms

In RAW 264.7 cells and colon epithelial cells, HT-29 is found that caffeic acid acts as an anti-inflammatory modulator by suppressing the production of nitric oxide (NO), IL-1, IL-6, IL-8, and TNF-, suggesting their potential therapeutic in IBD [365]

CRISPR screening raw sequencing data generated in this study has been deposited in the NCBI Gene Expression Omnibus (GEO) under accession number GSE261899