glutathione peroxidase serum levels in chicken peroxidases poultry biology: Part 1. Classification and mechanisms of action | World's Poultry Science Journal Importance of Antioxidants and Phytobiotics

A 70% decrease in tumor growth in a xenografted MV4-11 model was achieved when the mice were treated with 100 mg/kg curcumin in vivo

Additionally, glutathione disulfide (GSSG) plays a crucial role in managing oxidative stress in chronic illnesses by maintaining the balance between reduced and oxidized glutathione

The region-specific pattern of glutathione loss may also help guide future neuroimaging studies and more effective targeted therapies

Mechanistic insights suggest these effects are mediated through the modulation of metabolic and inflammatory pathways, including AMPK, NF-B, PPAR-, and VDR

Of note, the authors also showed a high expression level of TFRC in carcinoma tissues of patients with HER2+ breast cancer, but the regulatory machinery was not demonstrated in the study