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Description

Key regulatory axesincluding HIF-1, HHIP-PKM2, PTGES-AKT-HIF-1, and lactate/LDH-A (LDH5)-TGF-interact to collectively promote enhanced glycolysis and diminished oxidative metabolism, sustaining the pathological phenotype of the disease ( Abnormalities in the PPP are primarily manifested as oxidative stress-induced compensatory activation

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VLS-101, a ROR1-Targeting Antibody-Drug Conjugate, Demonstrates a Predictable Safety Profile and Clinical Efficacy in Patients with Heavily Pretreated Mantle Cell Lymphoma and Diffuse Large B-Cell Lymphoma

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Individuals recruited for a randomized, double-blind, placebo-controlled study were treated with RG (3.0 g/day) or placebo group for 4 weeks and, different parameters, including inflammatory markers, hormones, leukocyte, mtDNA-CN were evaluated

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Human exposure to PCBs occurs mostly via ingestion of contaminated food, but also via inhalation and dermal absorption

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Springer (2004)

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