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*Cytokines: Signaling molecules that mediate and regulate immunity, inflammation and hematopoiesis *TNF: Tumor necrosis factor

Green LC, Wagner DA, Glogowski J, Skipper PL, Wishnok JS, Tannenbaum SR

The systemic exposure is simply too low to drive a meaningful pharmacokinetic interaction

Therefore, early diagnosis by cystoscopy is justified in patients suspected to have Hunner lesions, without requiring them to fail other behavioral or medical treatments before recommending cystoscopy