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Any disruption to gastric physiology or transit time could theoretically affect this intricate absorption pathway

Proteostasis in Parkinsons disease: recent development and possible implication in diagnosis and therapeutics

[13] [16] For patients taking GLP-1/GIP medicinesparticularly those on concurrent metformin, following restricted diets, or with pre-existing malabsorption conditions proactive monitoring and management of B12 status should be considered an integral component of comprehensive care

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These results established cagrilintide as a clinically meaningful agent in its own right, while also confirming that its mechanism was distinct enough from existing therapies to warrant combination investigation