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Additionally, fibrosis reduces myocyte-myocyte coupling by decreasing Cx expression and promoting their redistribution away from the intercalated discz and hence increasing axial resistance resulting in slowed conduction velocity (195198)

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A thorough study in the British Medical Journal in 2018, which had followed over 9,000 people over 23 years, showed that both abstinence and drinking more than 14 units of alcohol a week, which is equivalent to a medium glass of wine (2.3 units) every day, also increases risk (22)

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