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This convergence of evidence underscores a shared pathophysiological thread where dysregulated microglial activity drives neural circuit dysfunction, making its pharmacological inhibition a rational cross-disease therapeutic approach

21 Beyond its role in inherited disease, B-crystallin also contributes to myocardial mechanics in acquired heart failure

Keep the tube tightly closed

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Moreover, some agents that have been used to interfere with p53 function are peptide-based, which would render them difficult to apply for brain senescence