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A common example of a Free Radical is a loose Oxygen ion

Trends Cancer 3(3):169180 Cormerais Y, Massard PA, Vucetic M et al (2018) The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5)

Huberman points to its neuroprotective properties as a reason to include it regularly

In the human blood group system, the O group [138], Duffy-negative [139], and Dantu blood group [140], all originate from pre-existing genetic polymorphisms, rather than de novo mutations that arose after the spread of malaria

Overall, because of the prevalence of inaccurate labeling and potential side effects, it may be safest to avoid this supplement altogether