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They can cross even more easily an inflamed, damaged one, and activate cytokine receptors on neurons (165), astrocytes (166) microglia (167), and brain mastocytes (168)

[DOI] [PubMed] [Google Scholar] 54.Brady D.C., Crowe M.S., Turski M.L., Hobbs G.A., Yao X., Chaikuad A., Knapp S., Xiao K., Campbell S.L., Thiele D.J., et al

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Because this is a neurodevelopmental condition, the brain still changes after birth, even into adulthood