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Cheli et al., 2020)

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For each 100 l of solvent A, 8.7 l of solvent B was then added and vortexed to neutralize the sample, and the mixture allowed to sit on dry ice for 20 min

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In recent years, intranasal delivery has attracted remarkable attention for brain targeting as the drug can be administered to the brain directly from the nose employing the trigeminal and olfactory pathways

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The initial dosing starts at 0.25 mg per week and is gradually increased at 4-week intervals to 0.5, 1.0, 1.7 mg, and finally to a maximum dose of 2.4 mg per week

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To investigate the effect of GHK on astrocytes following ICH, we evaluated the cell viability and cell proliferation in vitro by CCK-8 (Figures 3A,C), cytotoxicity by Lactate dehydrogenase (LDH) (Figure 3B)

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